Tacrolimus Capsule

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Therapeutic Indication

Prevention of organ transplant rejection
Heart transplant immunosuppression
Maintenance immunosuppressive therapy
Kidney transplant immunosuppression
Liver transplant immunosuppression
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Tacrolimus

Capsule

Tacrolimus Capsules are immunosuppressive medications used to help prevent organ rejection in patients undergoing organ transplantation. Tacrolimus works by suppressing the activity of the immune system, thereby reducing the risk of rejection of transplanted organs such as kidney, liver, or heart.
The formulation helps maintain immune balance and is commonly prescribed as part of long-term post-transplant immunosuppressive therapy under strict medical supervision.

Speciality Transplant Medicine | Immunology
Tags Immunosuppressant | Calcineurin Inhibitor | Transplant Care | Organ Rejection Prevention
Strength
  • Tacrolimus IP – 0.5 mg
  • Tacrolimus IP – 1 mg
  • Tacrolimus IP – 2 mg
Packing Size
  • 10 x 1 x 10

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Mechanism

Tacrolimus inhibits calcineurin activity in T-lymphocytes, thereby suppressing the production of inflammatory cytokines and reducing immune responses responsible for organ rejection.

Benefits

  • Helps maintain transplant stability under medical supervision
  • Supports long-term graft survival
  • Provides effective immunosuppressive control
  • Helps prevent organ transplant rejection

Side Effects

  • Tremors
  • Hyperglycemia
  • Headache

Contraindication

  • Hypersensitivity to Tacrolimus or macrolide antibiotics
  • Use with caution in severe hepatic impairment

Interaction

  • Nephrotoxic drugs: Increased risk of kidney toxicity
  • Grapefruit juice May increase blood concentration of Tacrolimus
  • CYP3A inhibitors: May increase Tacrolimus levels
  • CYP3A inducers: May reduce effectiveness

Warning and Precautions

This has been prescribed for the patient's specific condition. It may be dangerous to any other person.

  • Requires regular monitoring of Tacrolimus blood levels
  • Monitor kidney and liver function during therapy
  • Increased susceptibility to infections and malignancies may occur
  • Avoid self-medication or abrupt discontinuation
  • Use during pregnancy or lactation only under specialist supervision
  • Store in a cool, dry place away from sunlight

Disclaimer

All product details on this website are for reference and informational purposes only and are not directed at patients or consumers.
As a contract manufacturer, DM Pharma Pvt Ltd is not responsible for the marketing or end use of these products and disclaims all liability arising from reliance on this information.
Please consult a healthcare professional before using any medicinal product.